Jeuveau vs Botox often comes up when comparing anti-aging treatments. Both are FDA-approved neurotoxins for wrinkles that smooth fine lines by relaxing facial muscles, leaving your skin youthful and more refreshed.
Botox has been trusted for decades, while Jeuveau—often called “Newtox”—is a newer, more budget-friendly option. They use the same active ingredient, but they differ in cost, branding, and how results feel.
In this Botox vs Jeuveau comparison guide, we’ll talk about the similarities and differences of these treatments to help you choose. Our licensed aestheticians at Eau Claire Body Care also answered the most common questions clients ask about these injectable treatments.
MEDICALLY REVIEWED BY
Molly Rodriguez
15 years of experience
What is Botox?
Botox is the brand name for onabotulinumtoxinA, a purified protein first developed by Allergan. Allergan later became part of AbbVie, a leading global pharmaceutical company recognized for its work in aesthetics, neuroscience, and immunology.
Botox earned FDA approval in 1989 for medical use, followed by FDA clearance in 2002 for cosmetic treatment of frown lines.
Since then, Botox has become one of the most recognized injectables worldwide with the following uses:
Common Botox cosmetic uses include:
Reducing frown lines (glabellar lines between the brows)
Softening crow’s feet around the eyes
Lifting the brows for a more open look
Treating bunny lines on the nose
Reducing a gummy smile
Slimming the jawline by relaxing masseter muscles
Softening chin dimpling (“orange peel” chin)
FDA-approved Botox medical uses include:
Managing chronic migraines
Treating excessive sweating on the underarms (hyperhidrosis)
Reducing symptoms of an overactive bladder
Controlling cervical dystonia (neck muscle spasms)
Correcting certain eye muscle disorders
Off-label Botox medical uses (not FDA-approved):
Jaw clenching (bruxism, masseter hypertrophy)
Depression (studied but not FDA-cleared)
TMJ disorders
Scalp sweating, hands/feet sweating
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What is Jeuveau?
Jeuveau, also known by its scientific name prabotulinumtoxinA-xvfs, is a prescription neurotoxin created by Evolus and was FDA-approved in 2019. It was designed exclusively for cosmetic use, unlike Botox, which also has medical approvals.
The FDA only approved Jeuveau for the treatment of glabellar lines or the vertical frown lines that appear between your eyebrows. Unlike Botox, it does not carry FDA approval for other facial lines or medical conditions.
In general, Jeuveau is marketed as a more affordable option compared to Botox. The results are similar in softening wrinkles, but its positioning is aimed at younger patients who want value without sacrificing FDA-backed safety.
Because of its millennial-focused branding and lower cost, it quickly earned the nickname “NewTox.” In practice, some providers use it off-label for areas similar to Botox, but these uses are not FDA-cleared.
How do they work? (mechanism of action)
How Botox works
Botox is a neuromodulator made from botulinum toxin type A. It works by blocking acetylcholine, the neurotransmitter that signals your muscles to contract. When the signal is blocked, the targeted muscle relaxes, and the skin above it smooths out.
This mechanism makes Botox effective for frown lines, forehead lines, and crow’s feet. Because the muscle is temporarily at rest, your skin looks softer and more refreshed without changing your natural expression.
How Jeuveau works
Jeuveau works through the same neurotoxin mechanism. It also blocks acetylcholine, causing targeted muscle relaxation and smoother skin.
The only difference is that Jeuveau was developed exclusively for cosmetic use and approved only for treating glabellar lines (frown lines between your brows).
Key similarities between Jeuveau and Botox
Both Botox and Jeuveau are botulinum toxin type A neuromodulators. Whichever you choose, you’re getting precise wrinkle injections designed to soften lines without surgery temporarily.
Overall, the Jeuveau vs Botox procedure feels almost the same. Injections take only a few minutes, you don’t need anesthesia, and downtime is minimal. You can usually get treated over your lunch break and return to your day right away.
Still, you should remember that results are temporary for both Botox and Jeuveau. To maintain your wrinkle-free look, you’ll need touch-ups every three to six months.
Botox vs Jeuveau differences: key points
Botox vs Jeuveau differences include FDA approvals, onset, duration, cost, and scope of use.
Here’s a side-by-side comparison of their differences:
Category | Botox | Jeuveau |
FDA Approvals & Treatment Areas | Approved for frown lines, forehead, crow’s feet Approved for medical uses like migraines, hyperhidrosis, and certain bladder disorders. | Approved in 2019 for cosmetic use only, limited to glabellar lines (frown lines). |
Manufacturing & Formulation | Produced by AbbVie (Allergan) with long-established fermentation and purification methods. | Produced by Evolus with Hi-Pure™ purification and drying designed for aesthetic use. |
Onset of Results | Visible in 3–5 days; peak effect within about 2 weeks. | Results in 2–3 days; full effect also reaches around 2 weeks. |
Duration of Results | Typically lasts about 3–4 months. | Typically lasts about 3–5 months |
Cost | $10–$25 per unit $300–$600 per treatment. | $10–$16 per unit $250–$500 per treatment |
Effectiveness & Clinical Studies | Extensive decades-long data showing proven outcomes and high patient satisfaction across both cosmetic and multiple medical indications. | Clinical trials show comparable cosmetic results; some studies report slightly higher patient satisfaction at 30 days post-treatment. |
Side Effects & Risks | Common: mild redness, bruising, swelling, or headache. Rare: eyelid droop (ptosis) or allergic reactions. | Similar common mild effects |
FDA approvals & treatment areas
Botox has one of the broadest FDA approval records. It was cleared for cosmetic uses like forehead lines, crow’s feet, and frown lines, as well as medical conditions, including migraines, hyperhidrosis, and bladder disorders.
Meanwhile, Jeuveau, approved in 2019, is limited to cosmetic treatment of moderate to severe frown lines between the brows.
Manufacturing & formulation
The two products also differ in how they’re made. Botox, produced by AbbVie (formerly Allergan), undergo a fermentation and purification process refined over decades. Jeuveau, made by Evolus, uses a proprietary Hi-Pure™ purification and drying method.
These processes don’t change how your injections will work. Still, they cause differences in how much your treatment will cost.
Jeuveau vs Botox results onset
Jeuveau often delivers visible improvements within 2–3 days, which can feel like an advantage if you want quick results.
On the other hand, Botox usually takes 3–5 days to show initial changes. Both products reach their full effect at about two weeks, though some of our patients describe Jeuveau as slightly quicker.
Jeuveau vs Botox: duration of results
Botox generally lasts about 3–4 months, which has been consistent across decades of use. Meanwhile, Jeuveau may last a little longer for some patients, with effects reported up to 5 months in clinical studies.
Still, factors such as your metabolism, muscle strength, and activity level influence how long your results hold.
Jeuveau vs Botox cost comparison
Botox costs $10–$25 per unit, with full treatments ranging from $300–$600, depending on your injected area. Jeuveau is usually marketed 10% to 20% lower per unit, sometimes paired with promotional pricing or loyalty programs.
Overall, the final cost depends on the number of units needed rather than the number of injections.
Botox vs Jeuveau effectiveness & clinical studies
According to the FDA’s report on Jeuveau’s pivotal Phase III trials (EV-001 and EV-002), about 67.5 to 70.4% of patients showed a visible improvement in frown lines at Day 30 post-injection. These results are quite similar to those of established outcomes with Botox.
There’s also a 2024 clinical study published in Plastic and Reconstructive Surgery Global Open comparing Jeuveau and Botox directly. This double-blind randomized trial showed no meaningful difference in patient satisfaction at 90 days, with both products delivering strong cosmetic improvements.
Another 2020 study published at the National Library of Medicine found that Jeuveau is safe and effective for moderate to severe frown lines.
For you, these proven results mean both Botox and Jeuveau are equally effective choices when performed by skilled injectors like Eau Claire Body Care.
Botox vs Jeuveau side effects and risks
Both Botox and Jeuveau are relatively safe when administered by licensed and experienced injectors like Eau Claire Body Care. Most of our patients only experience mild and short-term side effects, with serious issues being extremely rare.
Below, we listed down some common side effects you may expect, so you’ll be prepared for your upcoming Botox or Jeuveau treatment:
Common side effects:
Redness or slight swelling at the injection site
Small bruises that fade within a few days
Temporary headache or tenderness
Mild discomfort right after treatment
Extremely rare risks (if done by a professional):
Eyelid droop (ptosis) if the product spreads into nearby muscles
Allergic reaction, such as itching, rash, or breathing difficulty
Infection at the injection site, though uncommon
When to avoid Botox and Jeuveau:
You’re pregnant or currently breastfeeding
You have certain neuromuscular conditions (like myasthenia gravis or ALS)
You’re allergic to botulinum toxin ingredients
Who is the best candidate?
Wondering if you’re the best candidate for Botox or the best candidate for Jeuveau? Here’s a quick guide to know which is the best neuromodulator treatment for you:
You’re the best candidate for BOTOX if…
You want treatment for multiple facial areas like frown lines, forehead, and crow’s feet.
You also need help with medical issues like migraines, excessive sweating, or muscle spasms.
You’re looking for treatment that balances both cosmetic and therapeutic benefits.
You prefer a product with a decades-long safety record and extensive clinical data.
You value predictable, consistent results backed by long-term FDA approvals.
You’re the best candidate for JEUVEAU if…
You’re mainly concerned about frown lines between your brows.
You want a more budget-friendly option with similar results.
You’re younger, new to neurotoxin treatments, or nervous about trying Botox first.
You prefer a product marketed for aesthetics, not medical conditions.
You want visible results quickly, often within 2–3 days.
What to expect during treatment
At Eau Claire Body Care, the process is simple and easy to follow. Here’s exactly what happens when you come in for a Botox or Jeuveau appointment:
Step 1: Consultation
If you haven’t had a consultation before, you’ll sit down with our injector to talk about your goals and medical history. Together, we decide on the best treatment plan for you.
Step 2: Preparation
Next, we’ll clean the injection site and apply a topical numbing cream to make your Botox or Jeuveau as comfy as possible.
Step 3: Injections
The treatment itself is quick. Injections take about 20–45 minutes, depending on the size and number of areas you want to treat.
Step 4: Aftercare tips
Right after your injections, we’ll advise you of the proper aftercare to ensure your Botox or Jeuveau will settle properly. We’ll also schedule you for a check-in consultation to ensure you’re getting the best results.
Results timeline & before/after expectations
Everyone responds a little differently to wrinkle treatments. Whether you choose Botox or Jeuveau, results can vary based on factors like your age, muscle strength, metabolism, and even how expressive your face is day to day.
The good news is that both options give you a smoother, refreshed look without the “frozen” effect when done by skilled injectors.
Here’s a quick wrinkle reduction timeline to keep you realistic with the Botox vs Jeuveau results:
Treatment | First Visible Results | Peak Results | Fade Timeline |
Jeuveau | 2–3 days | 1–2 weeks | 3–5 months |
Botox | 3–5 days | ~2 weeks | 3–4 months |
Jeuveau vs Botox before and after results
Here are some before-and-after results from our clients who tried Botox and Jeuveau at Eau Claire Body Care:
Combining treatments or alternatives
Can you use Botox and Jeuveau together? The answer is that you can rotate between them over time, but they shouldn’t be mixed in the same session.
Each of these neurotoxins has a slightly different formula, and combining them won’t improve results. What matters more is choosing the right option for your needs, which is something we walk through with you in detail.
There are also other FDA-approved neuromodulators, such as Dysport, Xeomin, and Daxxify. Like Botox and Jeaveau, these injectables are also made of the same botulinum toxin type A.
Here’s a side-by-side comparison of Botox, Jeuveau, Dysport, Xeomin, and Daxxify:
Product | FDA Approval | Onset of Results | Duration | Unique Features |
Botox | 2002 (cosmetic) | 3–5 days | 3–4 months | Most established; also approved for multiple medical uses |
Jeuveau | 2019 (cosmetic) | 2–3 days | 3–5 months | Marketed as “Newtox”; formulated specifically for aesthetic use |
2009 (cosmetic) | 2–3 days | 3–4 months | Tends to spread more easily; often used for larger treatment areas | |
Xeomin | 2011 (cosmetic) | 3–5 days | 3–4 months | “Naked” formulation with fewer additives; may reduce antibody formation risk |
Daxxify | 2022 (cosmetic) | ~1–2 days | 6–9 months | Currently the longest-lasting option available |
Learn more: Check our guide here about Dysport vs. Botox.
But when are fillers or lasers the better option?
Neurotoxins (like Botox and Jeuveau) work best for dynamic wrinkles — fine lines that only show with movement.
However, if your wrinkles are static or show up even without facial expressions, dermal fillers might be a better anti-aging treatment.
And if you have other skin issues aside from wrinkles, such as sunspots, acne scars, or enlarged pores, laser treatment can hit many birds with one stone.
Why trust Eau Claire Body Care for your anti-aging treatment?
At Eau Claire Body Care, we’ve helped 1,000+ clients achieve a younger look without surgery. Here’s why locals like you trust us, whether for Jeuveau or Botox in Eau Claire:
10+ years of cosmetic expertise
For over a decade, we’ve been providing not only neuromodulator injections, but a wide range of cosmetic treatments at affordable costs. Every treatment is tailored for you to ensure the best results.
Licensed and certified medical professionals
At Eau Claire Body Care, we’re a team of licensed aestheticians, RNs, cosmetologists, laser technicians, and concierge specialists dedicated to achieving your beauty goals.
Voted #1 trusted medical spa in Eau Claire
We’re the #1 medical spa in Eau Claire – not our words, but our clients’! We’ve been recognized as the #1 medical spa clinic in Eau Claire, Wisconsin, by VolumeOne’s The Best of the Chippewa Valley 2025 Reader Poll!
If you’re interested in Botox, Jeuveau, or other rejuvenating skin treatments, contact us at Eau Claire Body Care to learn more!
FAQs about Botox and Jeuveau
Is Jeuveau cheaper than Botox?
Yes, Jeuveau is typically less expensive than Botox. Botox costs about $12 to $20 per unit, while Jeuveau is typically 10 % to 20% less expensive. Pricing depends on how many units you need, the size of the injection site, and your muscle strength.
Which lasts longer, Botox or Jeuveau?
Botox lasts about 3 to 4 months, while Jeuveau may last 3 to 5 months, depending on each person. Duration varies by individual factors like age, metabolism, and muscle activity. For example, athletes or highly expressive individuals may notice results fade more quickly.
How many units of Botox do I need compared to Jeuveau?
The number of Botox units vs Jeuveau units needed is usually similar because they share the exact dosing conversion. Most patients need about 20 units for frown lines, but the actual dosage varies by muscle strength and treatment area.
Licensed injectors like Eau Claire Body Care will determine the exact units based on your face, goals, and safety guidelines.
Can I switch from Botox to Jeuveau?
Yes, you can switch from Botox to Jeuveau. Many patients rotate products over time without issues. Switching is often done for cost savings, to achieve a faster onset, or to try a newer formula.
Still, you should not mix them in one session, but alternating between Botox and Jeuveau across appointments is safe and common.
Can Jeuveau or Botox cause droopy eyelids?
Both Jeuveau and Botox rarely cause droopy eyelids (ptosis). This happens if the product spreads to nearby muscles, but the risk is low when injections are done by skilled providers.
Choosing a licensed injector significantly reduces the chance of experiencing eyelid droop or unwanted results.
Which is better for first-time users: Jeuveau or Botox?
For first-time users, Jeuveau is often chosen for its lower cost and quicker results, which are visible in 2 to 3 days. Botox may be preferred if you want a product with a longer safety history or need treatment for both cosmetic and medical issues. The best choice depends on your budget, goals, and comfort level.
How often should I get Jeuveau or Botox injections?
Most people need Jeuveau or Botox injections every 3–4 months, though Jeuveau may sometimes last up to 5 months in certain patients. Injection frequency depends on metabolism, muscle activity, and treatment goals.
